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Ph.D. Research

I did my Ph.D. work at UC San Diego in the Department of Chemistry & Biochemistry. As any biochemist knows, my Ph.D. work consisted of long days in the lab and sleepless nights wondering if I would ever discover anything worthy of a Ph.D. Luckily, my 6 years of hardwork in the Komives lab paid off!

My Ph.D. work focused on Protein Dynamics of IκBα and Thrombin-Thrombomodulin. If you need some bedtime reading, here are the links to some of the research papers:

  1. Long-range effects and functional consequences of stabilizing mutations in the ankyrin repeat domain of IκBα: Published in the Journal of Molecular Biology, 2012.
  2. Thrombomodulin Binding Selects the Catalytically Active Form of Thrombin: Published in Biochemistry, 2015.
  3. Protein Dynamics and Allostery in Thrombin, Thrombomodulin, and IkappaBalpha: My Ph.D. Thesis Published by UC San Diego, 2015.
  4. NMR reveals a dynamic allosteric pathway in thrombin Published in Nature Scientific Reports, 2017.